Microglia and AIDS

Bubien JK, Benveniste EN, Benos DJ (1995) HIV_gp120 activates large_conductance apamin_sensitive potassium channels in rat astrocytes. Am J Physiol 268:C1440_C1449

Buzy JM, Lindstrom LM, Zink MC, Clements JE (1995) HIV_1 in the developing CNS: developmental differences in gene expression. Virology 210:361_371

Ishimoto S, Fujimura Y, Yamanaka T, Shimoyama T, Nishida S, Matsuoka H, Nishikawa K, Yoshioka A, Narita N, Honda M, et al (1995) [An enzyme_linked immunosorbent assay determining anti_principal neutralizing determinant antibodies using synthetic peptides deduced from cDNA sequences of HIV_1 V3 loop domain]. Rinsho Ketsueki 36:193_199

Tyor WR, Wesselingh SL, Griffin JW, McArthur JC, Griffin DE (1995) Unifying hypothesis for the pathogenesis of HIV_associated dementia complex, vacuolar myelopathy, and sensory neuropathy. J Acquir Immune Defic Syndr Hum Retrovirol 9:379_388

Wilt SG, Milward E, Zhou JM, Nagasato K, Patton H, Rusten R, Griffin DE, O'Connor M, Dubois Dalcq M (1995) In vitro evidence for a dual role of tumor necrosis factor_alpha in human immunodeficiency virus type 1 encephalopathy. Ann Neurol 37:381_394

(1994) Neuro_AIDS. Proceedings of a workshop. Portland, Maine, August 16_19, 1993. Adv Neuroimmunol 4:145_336

(1994) Neuro_AIDS. Proceedings of a workshop. Portland, Maine, August 16_19, 1993. Adv Neuroimmunol 4:145_336

Benos DJ, Hahn BH, Bubien JK, Ghosh SK, Mashburn NA, Chaikin MA, Shaw GM, Benveniste EN (1994) Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc Natl Acad Sci U S A 91:494_498

Benos DJ, Hahn BH, Bubien JK, Ghosh SK, Mashburn NA, Chaikin MA, Shaw GM, Benveniste EN (1994) Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc Natl Acad Sci U S A 91:494_498

Benos DJ, Hahn BH, Shaw GM, Bubien JK, Benveniste EN (1994) gp120_mediated alterations in astrocyte ion transport. Adv Neuroimmunol 4:175_179

Benveniste EN (1994) Cytokine circuits in brain. Implications for AIDS dementia complex. Res Publ Assoc Res Nerv Ment Dis 72:71_88

Black R, Sager P (1994) Summary of workshop contributions.Third Workshop on NeuroAIDS. Adv Neuroimmunol 4:149_156

Blumberg BM, Gelbard HA, Epstein LG (1994) HIV_1 infection of the developing nervous system: central role of astrocytes in pathogenesis. Virus Res 32:253_267

Climent C, DeVinatea ML, Lasala G, Ie SO, Velez R, Colon L, Mullick FG (1994) Geographical pathology profile of AIDS in Puerto Rico: the first decade. Mod Pathol 7:647_651

Davis EJ, Foster TD, Thomas WE (1994) Cellular forms and functions of brain microglia. Brain Res Bull 34:73_78

Dickson DW, Lee SC, Hatch W, Mattiace LA, Brosnan CF, Lyman WD (1994) Macrophages and microglia in HIV_related CNS neuropathology. Res Publ Assoc Res Nerv Ment Dis 72:99_118

Gallo P, De Rossi A, Sivieri S, Chieco Bianchi L, Tavolato B (1994) M_CSF production by HIV_1_infected monocytes and its intrathecal synthesis. Implications for neurological HIV_1_related disease. J Neuroimmunol 51:193_198

Gelbard HA, Nottet HS, Swindells S, Jett M, Dzenko KA, Genis P, White R, Wang L, Choi YB, Zhang D, et al (1994) Platelet_activating factor: a candidate human immunodeficiency virus type 1_induced neurotoxin. J Virol 68:4628_4635

Gendelman HE, Genis P, Jett M, Zhai QH, Nottet HS (1994) An experimental model system for HIV_1_induced brain injury. Adv Neuroimmunol 4:189_193

Gendelman HE, Tardieu M (1994) Macrophages/microglia and the pathophysiology of CNS injuries in AIDS. J Leukoc Biol 56:387_388

Ho WZ, Cherukuri R, Douglas SD (1994) The macrophage and HIV_1. Immunol Ser 60:569_587

Lipton SA (1994) HIV_related neuronal injury. Potential therapeutic intervention with calcium channel antagonists and NMDA antagonists. Mol Neurobiol 8:181_196

Lipton SA (1994) Neuronal injury associated with HIV_1 and potential treatment with calcium_channel and NMDA antagonists. Dev Neurosci 16:145_151

Lipton SA, Yeh M, Dreyer EB (1994) Update on current models of HIV_related neuronal injury: platelet_activating factor, arachidonic acid and nitric oxide. Adv Neuroimmunol 4:181_188

Lipton SA (1994) AIDS_related dementia and calcium homeostasis. Ann N Y Acad Sci 747:205_224

Masliah E, Ge N, Achim CL, Wiley CA (1994) Cytokine receptor alterations during HIV infection in the human central nervous system. Brain Res 663:1_6

Mitrovic B, Martin FC, Charles AC, Ignarro LJ, Anton PA, Shanahan F, Merrill JE (1994) Neurotransmitters and cytokines in CNS pathology. Prog Brain Res 103:319_330

Nathanson N, Cook DG, Kolson DL, Gonzalez Scarano F (1994) Pathogenesis of HIV encephalopathy. Ann N Y Acad Sci 724:87_106

Nathanson N, Cook DG, Kolson DL, Gonzalez Scarano F (1994) Pathogenesis of HIV encephalopathy. Ann N Y Acad Sci 724:87_106

Petito CK, Vecchio D, Chen YT (1994) HIV antigen and DNA in AIDS spinal cords correlate with macrophage infiltration but not with vacuolar myelopathy. J Neuropathol Exp Neurol 53:86_94

Pulliam L, Clarke JA, McGuire D, McGrath MS (1994) Investigation of HIV_infected macrophage neurotoxin production from patients with AIDS dementia. Adv Neuroimmunol 4:195_198

Reyes E, Mohar A, Mallory M, Miller A, Masliah E (1994) Hippocampal involvement associated with human immunodeficiency virus encephalitis in Mexico. Arch Pathol Lab Med 118:1130_1134

Sinclair E, Gray F, Ciardi A, Scaravilli F (1994) Immunohistochemical changes and PCR detection of HIV provirus DNA in brains of asymptomatic HIV_positive patients. J Neuropathol Exp Neurol 53:43_50

Tabakoff B (1994) Alcohol and AIDS__is the relationship all in our heads? Alcohol Clin Exp Res 18:415_416

Tillmann M, Krebs FC, Wessner R, Pomeroy SM, Goodenow MM, Wigdahl B (1994) Neuroglial_specific factors and the regulation of retrovirus transcription. Adv Neuroimmunol 4:305_318

Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L (1994) Central nervous system damage produced by expression of the HIV_1 coat protein gp120 in transgenic mice. Nature 367:188_193

Weis S, Neuhaus B, Mehraein P (1994) Activation of microglia in HIV_1 infected brains is not dependent on the presence of HIV_1 antigens. Neuroreport 5:1514_1516

Banati RB, Kreutzberg GW (1993) Flow cytometry: measurement of proteolytic and cytotoxic activity of microglia. Clin Neuropathol 12:285_288

Boldorini R, Cristina S, Vago L, Tosoni A, Guzzetti S, Costanzi G (1993) Ultrastructural studies in the lytic phase of progressive multifocal leukoencephalopathy in AIDS patients. Ultrastruct Pathol 17:599_609

Epstein LG, Gendelman HE (1993) Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 33:429_436

Epstein LG, Gendelman HE (1993) Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 33:429_436

Hawkins CP, McLaughlin JE, Kendall BE, McDonald WI (1993) Pathological findings correlated with MRI in HIV infection. Neuroradiology 35:264_268

Hurtrel B, Chakrabarti L, Hurtrel M, Montagnier L (1993) Target cells during early SIV encephalopathy. Res Virol 144:41_46

Lacroix C, Vazeux R, Brousse N, Blanche S, Tardieu M (1993) [A neuropathological study of 10 HIV_infected children]. Rev Neurol Paris 149:37_45

Levi G, Patrizia M, Agresti C, Petrucci T, Bernardo A (1993) Use of rat microglial cells for the study of a possible mechanism of brain damage in AIDS. Clin Neuropathol 12:290_292

Nakajima K, Kohsaka S (1993) Functional roles of microglia in the brain. Neurosci Res 17:187_203

Neuen Jacob E, Arendt G, Wendtland B, Jacob B, Schneeweis M, Wechsler W (1993) Frequency and topographical distribution of CD68_positive macrophages and HIV_1 core proteins in HIV_associated brain lesions. Clin Neuropathol 12:315_324

Power C, Kong PA, Crawford TO, Wesselingh S, Glass JD, McArthur JC, Trapp BD (1993) Cerebral white matter changes in acquired immunodeficiency syndrome dementia: alterations of the blood_brain barrier. Ann Neurol 34:339_350

Power C, Kong PA, Crawford TO, Wesselingh S, Glass JD, McArthur JC, Trapp BD (1993) Cerebral white matter changes in acquired immunodeficiency syndrome dementia: alterations of the blood_brain barrier. Ann Neurol 34:339_350

Schielke E (1993) [HIV encephalopathy__clinical aspects, neuropathology and pathogenesis]. Nervenarzt 64:83_90

Ushijima H, Shibuya A (1993) [AIDS virus]. No To Hattatsu 25:156_162

Weidenheim KM, Epshteyn I, Lyman WD (1993) Immunocytochemical identification of T_cells in HIV_1 encephalitis: implications for pathogenesis of CNS disease. Mod Pathol 6:167_174

Wu E, Brosnan CF, Raine CS (1993) SP_40,40 immunoreactivity in inflammatory CNS lesions displaying astrocyte/oligodendrocyte interactions. J Neuropathol Exp Neurol 52:129_134

Artigas J, Bachler B, Habedank S, Taube F, Franz H, Niedobitek F (1992) Comparative lectinhistochemical studies on paraffin_ and glycol methacrylate_embedded CNS tissue specimens from AIDS autopsies. Mistletoe lectin I (ML I) as cell_marker. Zentralbl Pathol 138:272_277

Cornford ME, Holden JK, Boyd MC, Berry K, Vinters HV (1992) Neuropathology of the acquired immune deficiency syndrome (AIDS): report of 39 autopsies from Vancouver, British Columbia. Can J Neurol Sci 19:442_452

Masliah E, Achim CL, Ge N, DeTeresa R, Terry RD, Wiley CA (1992) Spectrum of human immunodeficiency virus_associated neocortical damage. Ann Neurol 32:321_329

Masliah E, Ge N, Achim CL, Hansen LA, Wiley CA (1992) Selective neuronal vulnerability in HIV encephalitis. J Neuropathol Exp Neurol 51:585_593

Peterson PK, Gekker G, Hu S, Schoolov Y, Balfour HHJ, Chao CC (1992) Microglial cell upregulation of HIV_1 expression in the chronically infected promonocytic cell line U1: the role of tumor necrosis factor_alpha. J Neuroimmunol 41:81_87

Sharpless N, Gilbert D, Vandercam B, Zhou JM, Verdin E, Ronnett G, Friedman E, Dubois Dalcq M (1992) The restricted nature of HIV_1 tropism for cultured neural cells. Virology 191:813_825

Sinclair E, Scaravilli F (1992) Detection of HIV proviral DNA in cortex and white matter of AIDS brains by non_isotopic polymerase chain reaction: correlation with diffuse poliodystrophy. AIDS 6:925_932

Wiestler OD, Leib SL, Brustle O, Spiegel H, Kleihues P (1992) Neuropathology and pathogenesis of HIV encephalopathies. Acta Histochem Suppl 42:107_114

Achim CL, Morey MK, Wiley CA (1991) Expression of major histocompatibility complex and HIV antigens within the brains of AIDS patients. AIDS 5:535_541

Dickson DW, Mattiace LA, Kure K, Hutchins K, Lyman WD, Brosnan CF (1991) Microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab Invest 64:135_156

Gray F, Haug H, Chimelli L, Geny C, Gaston A, Scaravilli F, Budka H (1991) Prominent cortical atrophy with neuronal loss as correlate of human immunodeficiency virus encephalopathy. Acta Neuropathol Berl 82:229_233

Kure K, Llena JF, Lyman WD, Soeiro R, Weidenheim KM, Hirano A, Dickson DW (1991) Human immunodeficiency virus_1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains. Hum Pathol 22:700_710

Lipton SA (1991) HIV_related neurotoxicity. Brain Pathol 1:193_199

Merrill JE, Chen IS (1991) HIV_1, macrophages, glial cells, and cytokines in AIDS nervous system disease. FASEB J 5:2391_2397

Poutiainen E, Haltia M, Elovaara I, Lahdevirta J, Iivanainen M (1991) Dementia associated with human immunodeficiency virus: subcortical or cortical? Acta Psychiatr Scand 83:297_301

Schlote W (1991) [HIV encephalopathy]. Verh Dtsch Ges Pathol 75:51_60

Vazeux R (1991) AIDS encephalopathy and tropism of HIV for brain monocytes/macrophages and microglial cells. Pathobiology 59:214_218

Aksamit AJ, Gendelman HE, Orenstein JM, Pezeshkpour GH (1990) AIDS_associated progressive multifocal leukoencephalopathy (PML): comparison to non_AIDS PML with in situ hybridization and immunohistochemistry. Neurology 40:1073_1078

Ciardi A, Sinclair E, Scaravilli F, Harcourt Webster NJ, Lucas S (1990) The involvement of the cerebral cortex in human immunodeficiency virus encephalopathy: a morphological and immunohistochemical study. Acta Neuropathol Berl 81:51_59

Cras P, Gheuens J, Lubke U, Boons J, Vandermeeren M, Van Heuverswijn H, Martin JJ (1990) A monoclonal antibody raised against Alzheimer cortex that specifically recognizes a subpopulation of microglial cells. J Histochem Cytochem 38:1201_1207

Dozic S, Suvakovic V, Cvetkovic D, Jevtovic D, Skender M (1990) Neoplastic angioendotheliomatosis (NAE) of the CNS in a patient with AIDS subacute encephalitis, diffuse leukoencephalopathy and meningo_cerebral cryptococcosis. Clin Neuropathol 9:284_289

Vazeux R, Cumont M, Girard PM, Nassif X, Trotot P, Marche C, Matthiessen L, Vedrenne C, Mikol J, Henin D, et al (1990) Severe encephalitis resulting from coinfections with HIV and JC virus. Neurology 40:944_948

Hirano A (1989) [Neuropathology of AIDS: Montefiore experience]. Rinsho Shinkeigaku 29:1546_1549

Kure K, Park YD, Kim TS, Lyman WD, Lantos G, Lee S, Cho S, Belman AL, Weidenheim KM, Dickson DW (1989) Immunohistochemical localization of an HIV epitope in cerebral aneurysmal arteriopathy in pediatric acquired immunodeficiency syndrome (AIDS). Pediatr Pathol 9:655_667

Pfister HW, Einhaupl KM, Wick M, Fateh Moghadam A, Huber M, Schielke E, Goebel FD, Matuschke A, Heinrich B, Bogner JR, et al (1989) Myelin basic protein in the cerebrospinal fluid of patients infected with HIV. J Neurol 236:288_291

Ferreiro J, Vinters HV (1988) Pathology of the pituitary gland in patients with the acquired immune deficiency syndrome (AIDS). Pathology 20:211_215