Microglia in Culture

Blevins G, Fedoroff S (1995) Microglia in colony_stimulating factor 1_deficient op/op mice. J Neurosci Res 40:535_544

Ryan RE, Sloane BF, Sameni M, Wood PL (1995) Microglial cathepsin B: an immunological examination of cellular and secreted species. J Neurochem 65:1035_1045

Yeung MC, Pulliam L, Lau AS (1995) The HIV envelope protein gp120 is toxic to human brain_cell cultures through the induction of interleukin_6 and tumor necrosis factor_alpha. AIDS 9:137_143

Gebicke Haerter PJ, Appel K, Taylor GD, Schobert A, Rich IN, Northoff H, Berger M (1994) Rat microglial interleukin_3. J Neuroimmunol 50:203_214

Hirose Y, Imai Y, Nakajima K, Takemoto N, Toya S, Kohsaka S (1994) Glial conditioned medium alters the expression of amyloid precursor protein in SH_SY5Y neuroblastoma cells. Biochem Biophys Res Commun 198:504_509

Maeda Y, Matsumoto M, Hori O, Kuwabara K, Ogawa S, Yan SD, Ohtsuki T, Kinoshita T, Kamada T, Stern DM (1994) Hypoxia/reoxygenation_mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival. J Exp Med 180:2297_2308

Masuda Nakagawa LM, Walz A, Brodbeck D, Neely MD, Grumbacher Reinert S (1994) Substrate_dependent interactions of leech microglial cells and neurons in culture. J Neurobiol 25:83_91

Nakajima K, Hamanoue M, Takemoto N, Hattori T, Kato K, Kohsaka S (1994) Plasminogen binds specifically to alpha_enolase on rat neuronal plasma membrane. J Neurochem 63:2048_2057

Neuhaus J, Fedoroff S (1994) Development of microglia in mouse neopallial cell cultures. Glia 11:11_17

Patrizio M, Levi G (1994) Glutamate production by cultured microglia: differences between rat and mouse, enhancement by lipopolysaccharide and lack effect of HIV coat protein gp120 and depolarizing agents. Neurosci Lett 178:184_189

Piani D, Fontana A (1994) Involvement of the cystine transport system xc_ in the macrophage_induced glutamate_dependent cytotoxicity to neurons. J Immunol 152:3578_3585

Schmidtmayer J, Jacobsen C, Miksch G, Sievers J (1994) Blood monocytes and spleen macrophages differentiate into microglia_like cells on monolayers of astrocytes: membrane currents. Glia 12:259_267

Sievers J, Schmidtmayer J, Parwaresch R (1994) Blood monocytes and spleen macrophages differentiate into microglia_like cells when cultured on astrocytes. Anat Anz 176:45_51

Steffan AM, Lafon ME, Gendrault JL, Koehren F, De Monte M, Royer C, Kirn A, Gut JP (1994) Feline immunodeficiency virus can productively infect cultured endothelial cells from cat brain microvessels. J Gen Virol 75:3647_3653

Vasilakos JP, Carroll RT, Emmerling MR, Doyle PD, Davis RE, Kim KS, Shivers BD (1994) Interleukin_1 beta dissociates beta_amyloid precursor protein and beta_amyloid peptide secretion. FEBS Lett 354:289_292

Colton CA, Keri JE, Chen WT, Monsky WL (1993) Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation. J Neurosci Res 35:297_304

Giulian D, Corpuz M, Chapman S, Mansouri M, Robertson C (1993) Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system. J Neurosci Res 36:681_693

Nagata K, Takei N, Nakajima K, Saito H, Kohsaka S (1993) Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain. J Neurosci Res 34:357_363

Nakajima K, Nagata K, Hamanoue M, Takemoto N, Kohsaka S (1993) Microglia_derived elastase produces a low_molecular_weight plasminogen that enhances neurite outgrowth in rat neocortical explant cultures. J Neurochem 61:2155_2163

Richardson A, Hao C, Fedoroff S (1993) Microglia progenitor cells: a subpopulation in cultures of mouse neopallial astroglia. Glia 7:25_33

Sacerdote P, Denis Donini S, Paglia P, Granucci F, Panerai AE, Ricciardi Castagnoli P (1993) Cloned microglial cells but not macrophages synthesize beta_endorphin in response to CRH activation. Glia 9:305_310

Whittle IR, Ironside JW, Piper IR, Miller JD (1993) Neuropathological and neurophysiological effects of interstitial white matter autologous and non_autologous protein containing solutions: further evidence for a glioma derived permeability factor. Acta Neurochir Wien 120:164_174

Bernton EW, Bryant HU, Decoster MA, Orenstein JM, Ribas JL, Meltzer MS, Gendelman HE (1992) No direct neuronotoxicity by HIV_1 virions or culture fluids from HIV_1_infected T cells or monocytes. AIDS Res Hum Retroviruses 8:495_503

Lauro GM, Fabrizi C, Businaro R, Fumagalli L, Torelli S, Gremo F (1992) Human astroglial but not microglial cells synthesize alpha 2_macroglobulin in vitro. Ital J Neurol Sci 13:661_665

Moore SC, McCormack JM, Armendariz E, Gatewood J, Walker WS (1992) Phenotypes and alloantigen_presenting activity of individual clones of microglia derived from the mouse brain. J Neuroimmunol 41:203_214

Nakajima K, Tsuzaki N, Nagata K, Takemoto N, Kohsaka S (1992) Production and secretion of plasminogen in cultured rat brain microglia. FEBS Lett 308:179_182

Nakajima K, Takemoto N, Kohsaka S (1992) Retinoic acid enhances the secretion of plasminogen from cultured rat microglia. FEBS Lett 314:167_170

Nakajima K, Shimojo M, Hamanoue M, Ishiura S, Sugita H, Kohsaka S (1992) Identification of elastase as a secretory protease from cultured rat microglia. J Neurochem 58:1401_1408

Vaca K, Wendt E (1992) Divergent effects of astroglial and microglial secretions on neuron growth and survival. Exp Neurol 118:62_72

Merrill JE (1991) Effects of interleukin_1 and tumor necrosis factor_alpha on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro. Dev Neurosci 13:130_137

Yoshida K, Gage FH (1991) Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res 538:118_126

Giulian D, Vaca K, Noonan CA (1990) Secretion of neurotoxins by mononuclear phagocytes infected with HIV_1. Science 250:1593_1596

Gebicke Haerter PJ, Bauer J, Schobert A, Northoff H (1989) Lipopolysaccharide_free conditions in primary astrocyte cultures allow growth and isolation of microglial cells. J Neurosci 9:183_194

Hunter SF, Bottenstein JE (1989) Bipotential glial progenitors are targets of neuronal cell line_derived growth factors. Brain Res Dev Brain Res 49:33_49

Northoff H, Bauer J, Schobert A, Flegel WA, Gebicke Haerter PJ (1989) Lipopolysaccharide (LPS)_free conditions allow growth and purification of postnatal brain macrophages (microglia). J Immunol Methods 116:147

Hetier E, Ayala J, Denefle P, Bousseau A, Rouget P, Mallat M, Prochiantz A (1988) Brain macrophages synthesize interleukin_1 and interleukin_1 mRNAs in vitro. J Neurosci Res 21:391_397

Omlin FX, Waldmeyer J (1986) Minisegments of newborn rat optic nerves in vitro: gliogenesis and myelination. Exp Brain Res 65:189_199

Lemke GE, Brockes JP (1983) Glial growth factor: a mitogenic polypeptide of the brain and pituitary. Fed Proc 42:2627_2629

Brockes JP, Lemke GE, Balzer DRJ (1980) Purification and preliminary characterization of a glial growth factor from the bovine pituitary. J Biol Chem 255:8374_8377