Microglia and Multiple Sclerosis

Cannella B, Raine CS (1995) The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 37:424_435

De Simone R, Giampaolo A, Giometto B, Gallo P, Levi G, Peschle C, Aloisi F (1995) The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions. J Neuropathol Exp Neurol 54:175_187

Hartung HP, Archelos JJ, Zielasek J, Gold R, Koltzenburg M, Reiners KH, Toyka KV (1995) Circulating adhesion molecules and inflammatory mediators in demyelination: a review. Neurology 45:S22_S32

Morgan TE, Laping NJ, Rozovsky I, Oda T, Hogan TH, Finch CE, Pasinetti GM (1995) Clusterin expression by astrocytes is influenced by transforming growth factor beta 1 and heterotypic cell interactions. J Neuroimmunol 58:101_110

Nyland H, Myhr KM (1995) [Multiple sclerosis]. Tidsskr Nor Laegeforen 115:2072_2077

Bo L, Mork S, Kong PA, Nyland H, Pardo CA, Trapp BD (1994) Detection of MHC class II_antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J Neuroimmunol 51:135_146

Johnson RT (1994) The virology of demyelinating diseases. Ann Neurol 36 Suppl:S54_S60

Johnson RT (1994) The virology of demyelinating diseases. Ann Neurol 36 Suppl:S54_S60

Mitrovic B, Martin FC, Charles AC, Ignarro LJ, Anton PA, Shanahan F, Merrill JE (1994) Neurotransmitters and cytokines in CNS pathology. Prog Brain Res 103:319_330

Newcombe J, Li H, Cuzner ML (1994) Low density lipoprotein uptake by macrophages in multiple sclerosis plaques: implications for pathogenesis. Neuropathol Appl Neurobiol 20:152_162

Porrini AM, Reder AT (1994) IFN_gamma, IFN_beta, and PGE1 affect monokine secretion: relevance to monocyte activation in multiple sclerosis. Cell Immunol 157:428_438

Raine CS (1994) Multiple sclerosis: immune system molecule expression in the central nervous system. J Neuropathol Exp Neurol 53:328_337

Scolding NJ, Zajicek JP, Wood N, Compston DA (1994) The pathogenesis of demyelinating disease. Prog Neurobiol 43:143_173

Ulvestad E, Williams K, Bjerkvig R, Tiekotter K, Antel J, Matre R (1994) Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen_presenting cells. J Leukoc Biol 56:732_740

Ulvestad E, Williams K, Vedeler C, Antel J, Nyland H, Mork S, Matre R (1994) Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgG. J Neurol Sci 121:125_131

Ulvestad E, Williams K, Mork S, Antel J, Nyland H (1994) Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J Neuropathol Exp Neurol 53:492_501

Ulvestad E, Williams K, Bo L, Trapp B, Antel J, Mork S (1994) HLA class II molecules (HLA_DR, _DP, _DQ) on cells in the human CNS studied in situ and in vitro. Immunology 82:535_541

Williams K, Ulvestad E, Antel JP (1994) B7/BB_1 antigen expression on adult human microglia studied in vitro and in situ. Eur J Immunol 24:3031_3037

Williams KC, Ulvestad E, Hickey WF (1994) Immunology of multiple sclerosis. Clin Neurosci 2:229_245

Compston A (1993) Limiting and repairing the damage in multiple sclerosis. Schweiz Med Wochenschr 123:1145_1152

Graeber MB (1993) Microglia, macrophages and the blood_brain barrier. Clin Neuropathol 12:296_297

Hartung HP (1993) Immune_mediated demyelination. Ann Neurol 33:563_567

Hartung HP (1993) Immune_mediated demyelination. Ann Neurol 33:563_567

Li H, Newcombe J, Groome NP, Cuzner ML (1993) Characterization and distribution of phagocytic macrophages in multiple sclerosis plaques. Neuropathol Appl Neurobiol 19:214_223

Woodroofe MN, Cuzner ML (1993) Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non_radioactive in situ hybridization. Cytokine 5:583_588

Wu E, Brosnan CF, Raine CS (1993) SP_40,40 immunoreactivity in inflammatory CNS lesions displaying astrocyte/oligodendrocyte interactions. J Neuropathol Exp Neurol 52:129_134

Merrill JE (1992) Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome. J Immunother 12:167_170

Sherman MP, Griscavage JM, Ignarro LJ (1992) Nitric oxide_mediated neuronal injury in multiple sclerosis. Med Hypotheses 39:143_146

Wiley CA, Johnson RT, Reingold SC (1992) Neurological consequences of immune dysfunction: lessons from HIV infection and multiple sclerosis. J Neuroimmunol 40:115_119

Cacabelos R, Barquero M, Garcia P, Alvarez XA, Varela de Seijas E (1991) Cerebrospinal fluid interleukin_1 beta (IL_1 beta) in Alzheimer's disease and neurological disorders. Methods Find Exp Clin Pharmacol 13:455_458

Esiri MM, Morris CS (1991) Immunocytochemical study of macrophages and microglial cells and extracellular matrix components in human CNS disease. 2. Non_neoplastic diseases. J Neurol Sci 101:59_72

Gray F, Chimelli L, Mohr M, Clavelou P, Scaravilli F, Poirier J (1991) Fulminating multiple sclerosis_like leukoencephalopathy revealing human immunodeficiency virus infection. Neurology 41:105_109

Merrill JE, Zimmerman RP (1991) Natural and induced cytotoxicity of oligodendrocytes by microglia is inhibitable by TGF beta. Glia 4:327_331

Selmaj K, Raine CS, Cannella B, Brosnan CF (1991) Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87:949_954

Adams CW, Poston RN (1990) Macrophage histology in paraffin_embedded multiple sclerosis plaques is demonstrated by the monoclonal pan_macrophage marker HAM_56: correlation with chronicity of the lesion. Acta Neuropathol Berl 80:208_211

Boyle EA, McGeer PL (1990) Cellular immune response in multiple sclerosis plaques. Am J Pathol 137:575_584

Ciardi A, Sinclair E, Scaravilli F, Harcourt Webster NJ, Lucas S (1990) The involvement of the cerebral cortex in human immunodeficiency virus encephalopathy: a morphological and immunohistochemical study. Acta Neuropathol Berl 81:51_59

Kesselring J (1990) [The pathogenesis of multiple sclerosis]. Schweiz Med Wochenschr 120:1083_1090

Lee SC, Moore GR, Golenwsky G, Raine CS (1990) Multiple sclerosis: a role for astroglia in active demyelination suggested by class II MHC expression and ultrastructural study. J Neuropathol Exp Neurol 49:122_136

Norton WT, Brosnan CF, Cammer W, Goldmuntz EA (1990) Mechanisms and suppression of inflammatory demyelination. Acta Neurobiol Exp Warsz 50:225_235

Clanet M, Blancher A, Calvas P, Rascol O (1989) Interferons and multiple sclerosis. Biomed Pharmacother 43:355_360

Lee SC, Raine CS (1989) Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules. J Neuroimmunol 25:261_266

Cuzner ML, Hayes GM, Newcombe J, Woodroofe MN (1988) The nature of inflammatory components during demyelination in multiple sclerosis. J Neuroimmunol 20:203_209

Hayes GM, Woodroofe MN, Cuzner ML (1988) Microglia express MHC class II in normal and demyelinating human white matter. Ann N Y Acad Sci 540:501_503

Hickey WF, Kimura H (1988) Perivascular microglial cells of the CNS are bone marrow_derived and present antigen in vivo. Science 239:290_292

Hayes GM, Woodroofe MN, Cuzner ML (1987) Microglia are the major cell type expressing MHC class II in human white matter. J Neurol Sci 80:25_37

Woodroofe MN, Bellamy AS, Feldmann M, Davison AN, Cuzner ML (1986) Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth. J Neurol Sci 74:135_152

Nyland H, Mork S, Matre R (1982) In_situ characterization of mononuclear cell infiltrates in lesions of multiple sclerosis. Neuropathol Appl Neurobiol 8:403_411

Nyland H, Matre R, Mork S (1980) Fc receptors of microglial lipophages in multiple sclerosis. N Engl J Med 302:120_121

Prineas JW, Wright RG (1978) Macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis. Lab Invest 38:409_421

Adams CW, Bayliss OB, Turner DR (1975) Phagocytes, lipid_removal and regression of atheroma. J Pathol 116:225_238